George A Stravodimos Selected Research

Phosphorylases (Glucan Phosphorylase)

4/2019	High Consistency of Structure-Based Design and X-Ray Crystallography: Design, Synthesis, Kinetic Evaluation and Crystallographic Binding Mode Determination of Biphenyl-N-acyl-β-d-Glucopyranosylamines as Glycogen Phosphorylase Inhibitors.
1/2018	Probing the β-pocket of the active site of human liver glycogen phosphorylase with 3-(C-β-d-glucopyranosyl)-5-(4-substituted-phenyl)-1, 2, 4-triazole inhibitors.
1/2017	van der Waals interactions govern C-β-d-glucopyranosyl triazoles' nM inhibitory potency in human liver glycogen phosphorylase.

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George A Stravodimos Research Topics

Disease

5	Type 2 Diabetes Mellitus (MODY) 04/2019 - 01/2015

Drug/Important Bio-Agent (IBA)

3	Liver GlycogenIBA 04/2019 - 01/2017
3	Phosphorylases (Glucan Phosphorylase)IBA 04/2019 - 01/2017
3	Pharmaceutical PreparationsIBA 04/2019 - 01/2017
2	Glycogen Phosphorylase (Phosphorylase, Glycogen)IBA 01/2017 - 01/2015
1	diphenyl (biphenyl)IBA 04/2019
1	glucopyranosylamineIBA 04/2019
1	GlycogenIBA 01/2018
1	EnzymesIBA 01/2018
1	ImidazolesIBA 01/2017
1	TriazolesIBA 01/2017
1	TriterpenesIBA 01/2017
1	PolyphenolsIBA 01/2017
1	FlavonoidsIBA 01/2017
1	Urea (Carbamide)FDA LinkGeneric 01/2015

Therapy/Procedure

1	Glycemic Control 01/2017